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What do systematic reviews say?

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Evidence found and GRADE certainty

4,317 questions · 75,239 findings · 5,342 reviews

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No studies found 15,213 · 20.2%GRADE not reported 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

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Zinc vs placebo

Risk of adverse events, including those that may be due to zinc supplements Duration of · adults and children with colds and/or upper respiratory infections
1 finding from 1 review

Zinc vs placebo

Risk of serious adverse events, including those that may be complications of the common cold · adults and children with colds and/or upper respiratory infections

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Endoscopic sphincterotomy vs sham

Proportion of participants without successful treatment at longest · adults with biliary sphincter of Oddi dysfunction

It is very uncertain whether summary of findings table ‐ Endoscopic sphincterotomy changes proportion of participants without successful treatment at longest compared with sham treatment (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy

Proportion of participants without successful treatment at 1 year · adults with biliary sphincter of Oddi dysfunction

It is very uncertain whether summary of findings table ‐ Biliary endoscopic sphincterotomy changes proportion of participants without successful treatment at 1 year compared with dual endoscopic sphincterotomy (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Endoscopic sphincterotomy vs sham

Proportion of participants with ≥ 1 serious adverse events at 1 year · adults with biliary sphincter of Oddi dysfunction

It is very uncertain whether summary of findings table ‐ Endoscopic sphincterotomy changes proportion of participants with ≥ 1 serious adverse events at 1 year compared with sham treatment (very low certainty).

1 finding from 1 review