Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

582 questions · 664 findings · 25 reviews · Endodontics and dental trauma

No studies found 111 · 16.7%GRADE not reported 417 · 62.8%Very low 69 · 10.4%Low 50 · 7.5%Moderate 16 · 2.4%High 1 · 0.2%

Biodentine vs Tempophore

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Biodentine showed no clear difference in radiological failure compared with tempophore; GRADE not reported.

1 finding from 1 review

Zinc oxide and eugenol (ZOE) vs Zinc oxide and propolis (ZOP)

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth

The review found no eligible studies for this question.

1 finding from 1 review

Self-etch adhesive + acetone-based total-etch adhesive vs Acetone-based total-etch adhesive

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes clinical failure compared with acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

Enamel matrix derivative (EMD) vs Calcium hydroxide (CH)

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    6 and 12 months
    Direct pulp capping; overall failure RR 1.00 (0.06 to 15.50) at 6/12 months (Garrocho-Rangel 2009); no pain/soft tissue/mobility/root resorption
    1 study · 90 participants
    GRADE not reported

3Mix (ciprofloxacin + metronidazole + minocycline) vs Ciprofloxacin + ornidazole + minocycline

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth

The review found no eligible studies for this question.

1 finding from 1 review

Glutaraldehyde + calcium hydroxide (CH) vs Full strength formocresol (FC)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in radiological failure compared with full strength formocresol (FC); GRADE not reported.

1 finding from 1 review

Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl) vs Calcium hydroxide + sodium hypochlorite (NaOCl)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) + sodium hypochlorite (NaOCl) showed no clear difference in radiological failure compared with calcium hydroxide + sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review