Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

729 questions · 775 findings · 58 reviews · Bone, Joint and Muscle Trauma

No studies found 166 · 21.4%GRADE not reported 24 · 3.1%Very low 356 · 45.9%Low 162 · 20.9%Moderate 47 · 6.1%High 20 · 2.6%

Timing of wound closure (immediate vs delayed)

Adverse events ‐ superficial infection · adults with open long bone fractures of the upper and lower limbs

It is very uncertain whether timing of wound closure (immediate changes adverse events ‐ superficial infection compared with delayed) (very low certainty).

1 finding from 1 review

Intervention not reported

Deep surgical site infection at 30 days or 90 days, or time points reported by study authors · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events: superficial infection · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures

It is very uncertain whether the intervention changes adverse events: superficial infection (very low certainty).

1 finding from 1 review