What do systematic reviews say?

GnRHa treatment vs danazol

GnRHas may leads to higher overall resolution ‐ Overall resolution/improvement compared with danazol (low certainty).

• Gonadotrophin‐releasing hormone analogues for pain associated with endometriosis 2010 · Cochrane Headline outcomes only
  RR 1.1 [1.01, 1.21]
  9 studies · 1046 participants
  Low

GnRHa treatment vs intra‐ uterine progestogen device

• Gonadotrophin‐releasing hormone analogues for pain associated with endometriosis 2010 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 129 participants
  Moderate

Excisional surgery vs Ablative surgery

Excisional surgery may leads to higher subsequent spontaneous conception compared with ablative surgery (low certainty).

• Excisional surgery versus ablative surgery for ovarian endometriomata 2008 · Cochrane Headline outcomes only
  OR 5.21 [2.04, 13.29]
  2 studies · 88 participants
  Low

Excisional surgery vs Ablative surgery

It is very uncertain whether excisional surgery changes pregnancy rate after controlled ovarian hyperstimulation compared with ablative surgery (very low certainty).

• Excisional surgery versus ablative surgery for ovarian endometriomata 2008 · Cochrane Headline outcomes only
  OR 1.4 [0.47, 4.15]
  1 study · 65 participants
  Very low

Cryopreservation vs fresh embryos transfer

Cryopreservation showed no clear difference in moderate and or severe OHSS compared with fresh embryos transfer (low certainty).

• Embryo freezing for preventing ovarian hyperstimulation syndrome 2007 · Cochrane Headline outcomes only
  OR 0.12 [0.01, 2.29]
  1 study · 125 participants
  Low

Cryopreservation vs fresh embryos transfer

Cryopreservation showed no clear difference in clinical pregnancies compared with fresh embryos transfer (low certainty).

• Embryo freezing for preventing ovarian hyperstimulation syndrome 2007 · Cochrane Headline outcomes only
  OR 1.08 [0.54, 2.19]
  1 study · 125 participants
  Low

Cryopreservation vs fresh embryos transfer

Cryopreservation showed no clear difference in number of livebirths (livebirth rate) compared with fresh embryos transfer (low certainty).

• Embryo freezing for preventing ovarian hyperstimulation syndrome 2007 · Cochrane Headline outcomes only
  OR 1.03 [0.5, 2.12]
  1 study · 125 participants
  Low

Cryopreservation vs albumin

It is very uncertain whether cryopreservation changes moderate and or severe OHSS compared with intra‐venous albumin (very low certainty).

• Embryo freezing for preventing ovarian hyperstimulation syndrome 2007 · Cochrane Headline outcomes only
  OR 5.33 [0.51, 56.24]
  1 study · 26 participants
  Very low

Cryopreservation vs albumin

Cryopreservation showed no clear difference in nil and or mild OHSS compared with intra‐venous albumin (low certainty).

• Embryo freezing for preventing ovarian hyperstimulation syndrome 2007 · Cochrane Headline outcomes only
  OR 0.38 [0.08, 1.9]
  1 study · 26 participants
  Low

Cryopreservation vs albumin

Cryopreservation showed no clear difference in clinical pregnancies compared with intra‐venous albumin (low certainty).

• Embryo freezing for preventing ovarian hyperstimulation syndrome 2007 · Cochrane Headline outcomes only
  OR 0.06 [0, 1.17]
  1 study · 26 participants
  Low