Findings

What do systematic reviews say?

4,860 questions · 64,864 findings · 4,913 reviews · Headline outcomes only

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No studies found 13,869 · 21.4%GRADE not reported 3,491 · 5.4%Very low 16,300 · 25.1%Low 17,338 · 26.7%Moderate 10,900 · 16.8%High 2,966 · 4.6%

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IVF vs IUI + ovarian stimulation with gonadotropins or CC

Clinical pregnancy rate · women with unexplained subfertility

IVF showed no clear difference in clinical pregnancy rate per woman randomised compared with IUI + ovarian stimulation with gonadotropins or CC (low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 1.17 [0.85, 1.59]
3 studies · 731 participants
Low

IVF vs IUI + ovarian stimulation with gonadotropins or CC

Multiple pregnancy rate · women with unexplained subfertility

IVF showed no clear difference in multiple pregnancy rate per woman randomised compared with IUI + ovarian stimulation with gonadotropins or CC (low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 0.82 [0.38, 1.77]
3 studies · 731 participants
Low

IVF vs IUI + ovarian stimulation with gonadotropins or CC

OHSS · women with unexplained subfertility

It is very uncertain whether IVF changes OHSS rate per woman randomised compared with IUI + ovarian stimulation with gonadotropins or CC (very low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 6.86 [0.35, 134.59]
1 study · 207 participants
Very low

IVF vs IUI + ovarian stimulation with gonadotropins or CC

Miscarriage · women with unexplained subfertility

It is very uncertain whether IVF changes miscarriage rate per woman randomised compared with IUI + ovarian stimulation with gonadotropins or CC (very low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 0.31 [0.03, 3.04]
1 study · 207 participants
Very low

IVF vs expectant management

Clinical pregnancy rate · women with unexplained subfertility

It is very uncertain whether IVF changes clinical pregnancy rate per woman randomised compared with expectant management (very low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 3.24 [1.07, 9.8]
2 studies · 86 participants
Very low

IVF vs expectant management

Multiple pregnancy rate · women with unexplained subfertility

The review found no eligible studies for this question.

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IVF vs expectant management

OHSS · women with unexplained subfertility

The review found no eligible studies for this question.

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IVF vs expectant management

Miscarriage · women with unexplained subfertility

The review found no eligible studies for this question.

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IVF vs unstimulated IUI

Live birth rate per woman · women with unexplained subfertility

IVF may leads to higher live birth rate per woman randomised compared with unstimulated IUI (low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 2.47 [1.19, 5.12]
2 studies · 156 participants
Low

IVF vs unstimulated IUI

Clinical pregnancy rate · women with unexplained subfertility

It is very uncertain whether IVF changes clinical pregnancy rate per woman randomised compared with unstimulated IUI (very low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 4.83 [0.94, 24.95]
1 study · 43 participants
Very low

IVF vs unstimulated IUI

Multiple pregnancy rate · women with unexplained subfertility

It is very uncertain whether IVF changes multiple pregnancy rate per woman randomised compared with unstimulated IUI (very low certainty).

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
OR 1.03 [0.04, 27.29]
1 study · 43 participants
Very low

IVF vs unstimulated IUI

OHSS · women with unexplained subfertility

The review found no eligible studies for this question.

1 finding from 1 review

In vitro fertilisation for unexplained subfertility 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Anger management vs waiting list control

Aggressive behaviour: severity of incidents: Aberrant Behaviour Checklist (ABC – irritability subscale – key worker report – post‐treatment (Analysis 1.2.1) · outwardly aggressive behaviour in people with intellectual disability

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 158 participants
Moderate

Summary of findings table ‐ Positive behavioural support vs treatment

Mental state: Common Mental Disorder (CMD) – at 6 months (Analysis 2.2.1) (CMD) · outwardly aggressive behaviour in people with intellectual disability

Summary of findings table ‐ Positive behavioural support showed no clear difference in mental state: Common Mental Disorder (CMD) – at 6 months (Analysis… compared with treatment (low certainty).

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
OR 1.44 [0.83, 2.49]
1 study · 215 participants
Low

Summary of findings table ‐ Positive behavioural support vs treatment

Quality of life ‐ not measured · outwardly aggressive behaviour in people with intellectual disability

The review found no eligible studies for this question.

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Positive behavioural support vs treatment

Cost of service utilisation · outwardly aggressive behaviour in people with intellectual disability

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 225 participants
Very low

Summary of findings table ‐ Meditation based on mindfulness vs treatment

Physical aggression · outwardly aggressive behaviour in people with intellectual disability

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Summary of findings table ‐ Meditation based on mindfulness vs treatment

Ability to control anger ‐ not measured · outwardly aggressive behaviour in people with intellectual disability

The review found no eligible studies for this question.

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Meditation based on mindfulness vs treatment

Adaptive functioning ‐ not measured · outwardly aggressive behaviour in people with intellectual disability

The review found no eligible studies for this question.

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Meditation based on mindfulness vs treatment

Mental state ‐ not measured · outwardly aggressive behaviour in people with intellectual disability

The review found no eligible studies for this question.

1 finding from 1 review

Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found