Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,811 questions · 70,850 findings · 5,139 reviews

No studies found 15,174 · 21.4%GRADE not reported 6,479 · 9.1%Very low 17,330 · 24.5%Low 17,814 · 25.1%Moderate 11,056 · 15.6%High 2,997 · 4.2%

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Intralesional triamcinolone vs Intralesional salvianolic acid B

Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)

It is very uncertain whether intralesional triamcinolone changes maximal mouth opening (interincisal distance) compared with intralesional salvianolic acid B (very low certainty).

1 finding from 1 review

Silver diamine fluoride (SDF) vs Atraumatic restorative treatment (ART) with glass ionomer cement (GIC) or glass ionomer material

Aesthetics · Children and adults (with or without carious lesions)
1 finding from 1 review

SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)

Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review

Part-time clear plastic (removable) retainer vs Any type of fixed (bonded) retainer

Adverse effects on oral health: Gingival Index (lower arch) · People who had received fixed appliance orthodontic treatment

It is very uncertain whether part-time clear plastic (removable) retainer changes adverse effects on oral health: Gingival Index (lower arch) compared with any type of fixed (bonded) retainer (very low certainty).

1 finding from 1 review

Fibre-reinforced composite fixed (bonded) retainer vs Multistrand / spiral wire fixed (bonded) retainer

Patient satisfaction (measured by patient satisfaction or aesthetic scales) · People who had received fixed appliance orthodontic treatment

It is very uncertain whether fibre-reinforced composite fixed (bonded) retainer changes patient satisfaction: aesthetics (VAS 0-10 cm, lower arch) compared with multistrand / spiral wire fixed (bonded) retainer (very low certainty).

1 finding from 1 review

Part-time clear plastic (removable) retainer vs Any type of fixed (bonded) retainer

Stability: Little's Irregularity Index (lower arch) · People who had received fixed appliance orthodontic treatment

It is very uncertain whether part-time clear plastic (removable) retainer changes stability: Little's Irregularity Index (lower arch) compared with any type of fixed (bonded) retainer (very low certainty).

1 finding from 1 review

Surgery vs Radiotherapy alone

Adverse events associated with treatment · Adults with oropharyngeal cancer
1 finding from 1 review

Upper clear plastic retainer + lower fixed canine-to-canine retainer vs Upper clear plastic retainer + lower interproximal reduction (adjunctive), no lower retainer

Stability: Little's Irregularity Index (lower arch) · People who had received fixed appliance orthodontic treatment

Upper clear plastic retainer + lower fixed canine-to-canine retainer showed no clear difference in stability: Little's Irregularity Index (lower arch) compared with upper clear plastic retainer + lower interproximal reduction…; GRADE not reported.

1 finding from 1 review

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Costs · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances

The review found no eligible studies for this question.

1 finding from 1 review

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

Discomfort/pain · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

It is very uncertain whether light-emitting diode (LED) photobiomodulation changes patient perception of pain and discomfort (VAS 0 to 100 mm) compared with conventional orthodontic appliance treatment (very low certainty).

1 finding from 1 review

Elective radical (comprehensive) neck dissection vs Elective selective neck dissection

Total mortality · Adults with oral cavity cancer
1 finding from 1 review

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Change in angulation of teeth adjacent to the space (molar and canine tipping/rotation) · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances
1 finding from 1 review