Findings

What do systematic reviews say?

2,510 questions · 2,653 findings · 194 reviews · Gynaecology and Fertility

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No studies found 531 · 20%GRADE not reported 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Black cohosh vs placebo

Vasomotor symptoms: hot flush intensity · patients with menopausal symptoms

1 finding from 1 review

Black cohosh (Cimicifuga spp.) for menopausal symptoms 2012 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 214 participants
Moderate

Black cohosh vs placebo

Vasomotor symptoms: night sweats · patients with menopausal symptoms

1 finding from 1 review

Black cohosh (Cimicifuga spp.) for menopausal symptoms 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 164 participants
Moderate

Black cohosh vs placebo

Menopausal Symptom Score · patients with menopausal symptoms

1 finding from 1 review

Black cohosh (Cimicifuga spp.) for menopausal symptoms 2012 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 357 participants
Moderate

Black cohosh vs placebo

Adverse events · patients with menopausal symptoms

Black cohosh showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review

Black cohosh (Cimicifuga spp.) for menopausal symptoms 2012 · Cochrane Headline outcomes only
RR 1.04 [0.82, 1.32]
2 studies · 344 participants
Low

Intervention not reported

Relief of bleedingPictorial bleeding charts · patients with uterine fibroids

The intervention may leads to higher relief of bleedingPictorial bleeding charts (low certainty).

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
OR 17.84 [6.72, 47.38]
2 studies · 77 participants
Low

Mifepristone (50 mg/1 day after/3 months) vs placebo

Leiomyoma volume (mL) · patients with uterine fibroids

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Low

Mifepristone (50 mg/1 day after/3 months) vs placebo

Cystic glandular dilatationdichotomic · patients with uterine fibroids

Mifepristone (50 mg/1 day after/3 months) may leads to higher cystic glandular dilatationdichotomic compared with placebo (low certainty).

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
OR 16.67 [1.36, 204.03]
1 study · 19 participants
Low

Mifepristone (5 mg/day/6 months) vs placebo

Relief of bleedingdichotomic · patients with uterine fibroids

Mifepristone (5 mg/day/6 months) showed no clear difference in relief of bleedingdichotomic compared with placebo (low certainty).

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
OR 2.22 [0.54, 9.13]
1 study · 42 participants
Low

Mifepristone (5 mg/day/6 months) vs placebo

Leiomyoma volume (mL) · patients with uterine fibroids

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 37 participants
Low

Mifepristone (5 mg/day/6 months) vs placebo

Uterine volume (cm³) · patients with uterine fibroids

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 37 participants
Low

Intervention not reported

Reduction in average fibroid volumeScale from: 0 to 100 · patients with uterine fibroids

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 99 participants
Low

Intervention not reported

Reduction in uterine volumeScale from: 0 to 100 · patients with uterine fibroids

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 72 participants
Low

Intervention not reported

Adverse events · patients with uterine fibroids

The intervention may leads to higher adverse events (low certainty).

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
OR 31.65 [4.83, 207.35]
2 studies · 54 participants
Low

Mifepristone (10 mg/day/3 months) vs placebo

Leiomyoma volume (mL) · patients with uterine fibroids

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 35 participants
Low

Mifepristone (10 mg/day/3 months) vs placebo

Uterine volume (cm³) · patients with uterine fibroids

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 35 participants
Low

Mifepristone (10 mg/day/3 months) vs placebo

Relief of bleedingdichotomic · patients with uterine fibroids

Mifepristone (10 mg/day/3 months) may leads to higher relief of bleedingdichotomic compared with placebo (low certainty).

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
OR 27.02 [7.25, 100.7]
1 study · 35 participants
Low

Mifepristone (10 mg/day/3 months) vs placebo

Relief of pelvic paindichotomic · patients with uterine fibroids

Mifepristone (10 mg/day/3 months) showed no clear difference in relief of pelvic paindichotomic compared with placebo (low certainty).

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
OR 2.1 [0.38, 11.71]
1 study · 26 participants
Low

Mifepristone (10 mg/day/3 months) vs placebo

Relief of dysmenorrhoeadichotomic · patients with uterine fibroids

Mifepristone (10 mg/day/3 months) may leads to higher relief of dysmenorrhoeadichotomic compared with placebo (low certainty).

1 finding from 1 review

Mifepristone for uterine fibroids 2012 · Cochrane Headline outcomes only
OR 10.93 [2.37, 50.51]
1 study · 26 participants
Low

Embryo culture with low oxygen concentration vs embryo culture with atmospheric oxygen concentration

Live birth rate · Patients with live birth rate

Embryo culture with low oxygen concentration probably leads to higher live birth rate compared with embryo culture with atmospheric oxygen concentration (moderate certainty).

1 finding from 1 review

Low oxygen concentrations for embryo culture in assisted reproductive technologies 2012 · Cochrane Headline outcomes only
OR 1.39 [1.11, 1.76]
3 studies · 1291 participants
Moderate

Embryo culture with low oxygen concentration vs embryo culture with atmospheric oxygen concentration

Ongoing pregnancy · Patients with ongoing pregnancy

Embryo culture with low oxygen concentration probably leads to higher ongoing pregnancy rate compared with embryo culture with atmospheric oxygen concentration (moderate certainty).

1 finding from 1 review

Low oxygen concentrations for embryo culture in assisted reproductive technologies 2012 · Cochrane Headline outcomes only
OR 1.4 [1.11, 1.77]
3 studies · 1291 participants
Moderate