Findings

What do systematic reviews say?

2,293 questions · 2,395 findings · 172 reviews · Gut

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No studies found 420 · 17.5%GRADE not reported 60 · 2.5%Very low 821 · 34.3%Low 602 · 25.1%Moderate 397 · 16.6%High 95 · 4%

Oral ondansetron (weight based) vs placebo

Revisit rate · patients with vomiting related to acute gastroenteritis with mild to moderate dehydration

Oral ondansetron (weight based) showed no clear difference in revisit rate compared with placebo (low certainty).

1 finding from 1 review

Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents 2011 · Cochrane Headline outcomes only
RR 1.09 [0.66, 1.79]
3 studies · 460 participants
Low

Intervention not reported

Quality of life (3 to 8 months) · patients with treatment of inflammatory bowel disease

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 173 participants
Very low

Intervention not reported

Depression and anxiety at 3 to 8 months ‐ Anxiety · patients with treatment of inflammatory bowel disease

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Very low

Intervention not reported

Quality of life (3 to 8 months) · patients with treatment of inflammatory bowel disease

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 596 participants
Very low

Intervention not reported

Quality of life (9 to 18 months) · patients with treatment of inflammatory bowel disease

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 947 participants
Very low

Intervention not reported

Depression (3 to 8 months) · patients with treatment of inflammatory bowel disease

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 430 participants
Very low

Intervention not reported

Depression (9 to 18 months) · patients with treatment of inflammatory bowel disease

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 378 participants
Very low

Intervention not reported

Not in remission at/during month 3 to 8 · patients with treatment of inflammatory bowel disease

It is very uncertain whether the intervention changes not in remission at/during month 3 to 8 (very low certainty).

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
OR 1.35 [0.73, 2.48]
3 studies · 221 participants
Very low

Intervention not reported

Not in remission at/during month 9 to 18 · patients with treatment of inflammatory bowel disease

It is very uncertain whether the intervention changes not in remission at/during month 9 to 18 (very low certainty).

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
OR 1 [0.65, 1.53]
3 studies · 434 participants
Very low

Intervention not reported

Quality of life (9 to 18 months) · patients with treatment of inflammatory bowel disease

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 235 participants
Very low

Intervention not reported

Depression (3 to 8 months) · patients with treatment of inflammatory bowel disease

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 219 participants
Very low

Intervention not reported

Depression (9 to 18 months) · patients with treatment of inflammatory bowel disease

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 266 participants
Very low

Intervention not reported

Not in remission at/during month 3 to 8 · patients with treatment of inflammatory bowel disease

It is very uncertain whether the intervention changes not in remission at/during month 3 to 8 (very low certainty).

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
OR 1.25 [0.58, 2.71]
3 studies · 182 participants
Very low

Intervention not reported

Not in remission at/during month 9 to 18 · patients with treatment of inflammatory bowel disease

It is very uncertain whether the intervention changes not in remission at/during month 9 to 18 (very low certainty).

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
OR 0.85 [0.48, 1.48]
5 studies · 287 participants
Very low

Intervention not reported

Quality of life and coping at 3 to 8 months ‐ Quality of life · patients with treatment of inflammatory bowel disease

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 71 participants
Very low

Intervention not reported

Quality of life and coping at 3 to 8 months ‐ Coping · patients with treatment of inflammatory bowel disease

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 69 participants
Very low

Intervention not reported

Depression and anxiety at 3 to 8 months ‐ Depression · patients with treatment of inflammatory bowel disease

1 finding from 1 review

Psychological interventions for treatment of inflammatory bowel disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 41 participants
Very low

GM-CSF vs placebo

Induction of clinical remission (CDAI < or = 150) · induction of remission in Crohn's disease

GM‐CSF showed no clear difference in induction of clinical remission (CDAI < or = 150) compared with placebo (low certainty).

1 finding from 1 review

Sargramostim (GM‐CSF) for induction of remission in Crohn's disease 2011 · Cochrane Headline outcomes only
RR 1.67 [0.8, 3.5]
3 studies · 537 participants
Low

GM-CSF vs placebo

Induction of 100‐point clinical response · induction of remission in Crohn's disease

GM‐CSF showed no clear difference in induction of 100‐point clinical response compared with placebo (low certainty).

1 finding from 1 review

Sargramostim (GM‐CSF) for induction of remission in Crohn's disease 2011 · Cochrane Headline outcomes only
RR 1.71 [0.98, 2.97]
3 studies · 537 participants
Low

GM-CSF vs placebo

Induction of 70‐point clinical response CDAI · induction of remission in Crohn's disease

GM‐CSF showed no clear difference in induction of 70‐point clinical response compared with placebo (low certainty).

1 finding from 1 review

Sargramostim (GM‐CSF) for induction of remission in Crohn's disease 2011 · Cochrane Headline outcomes only
RR 1.23 [0.83, 1.82]
1 study · 124 participants
Low