Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,510 questions · 2,653 findings · 194 reviews · Gynaecology and Fertility

No studies found 531 · 20%GRADE not reported 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

DHEA vs placebo or control

Side effects (androgenic overall combined with acne) number of events · Women in the peri‐ or postmenopausal phase

DHEA probably leads to higher side effects (androgenic overall combined with acne) number of events compared with control (placebo or no treatment) (moderate certainty).

1 finding from 1 review

Oral DHEA vs control subgrouped by differing routes of administration

Side effects: acne ‐ skin application · Women in the peri‐ or postmenopausal phase

It is very uncertain whether oral DHEA changes side effects: acne ‐ skin application compared with control subgrouped by differing routes of administration (very low certainty).

1 finding from 1 review

Oral DHEA vs control subgrouped by differing routes of administration

Side effects: acne ‐ oral administration · Women in the peri‐ or postmenopausal phase

It is very uncertain whether oral DHEA changes side effects: acne ‐ oral administration compared with control subgrouped by differing routes of administration (very low certainty).

1 finding from 1 review

Laparoscopic myomectomy vs open myomectomy (all types)

Perioperative in‐hospital adverse events; unscheduled return to theatre · women with uterine fibroids

Laparoscopic myomectomy showed no clear difference in perioperative in‐hospital adverse events; unscheduled return to… compared with open myomectomy (all types) (low certainty).

1 finding from 1 review