Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,811 questions · 70,850 findings · 5,139 reviews

No studies found 15,174 · 21.4%GRADE not reported 6,479 · 9.1%Very low 17,330 · 24.5%Low 17,814 · 25.1%Moderate 11,056 · 15.6%High 2,997 · 4.2%

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Favipiravir vs no treatment, supportive treatment, or other antiviral treatment

All‐cause mortality – at 28 to 30 days, or in‐hospital · people with confirmed COVID‐19

It is very uncertain whether favipiravir changes all‐cause mortality – at 28 to 30 days, or in‐hospital compared with no treatment, supportive treatment, or other antiviral treatment (very low certainty).

1 finding from 1 review

Favipiravir vs no treatment, supportive treatment, or other antiviral treatment

Clinical worsening: need for invasive mechanical ventilation up to 14 days  · people with confirmed COVID‐19

It is very uncertain whether favipiravir changes progression to invasive mechanical ventilation compared with no treatment, supportive treatment, or other antiviral treatment (very low certainty).

1 finding from 1 review

Favipiravir vs no treatment, supportive treatment, or other antiviral treatment

Time to clinical improvement (defined as time to a 2‐point reduction in patients’ admission status on WHO’s ordinal scale) · people with confirmed COVID‐19

It is very uncertain whether favipiravir changes time to clinical improvement (defined as time to a 2‐point reduction… compared with no treatment, supportive treatment, or other antiviral treatment (very low certainty).

1 finding from 1 review

Vitamin A vs placebo

Incidence of acute URTIs during the study period (the number of acute URTIs over a period of time) · children up to the age of 7 at risk of upper respiratory tract infection

Summary of findings table ‐ Vitamin A supplements showed no clear difference in incidence of acute URTIs during the study period (the number of… compared with placebo (low certainty).

1 finding from 1 review