What do systematic reviews say?

Intervention not reported

It is very uncertain whether the intervention changes the rate of complete remission and partly remission (very low certainty).

• Chinese herbal medicines for induction of remission in advanced or late gastric cancer 2013 · Cochrane Headline outcomes only
  OR 1.48 [0.78, 2.81]
  3 studies · 153 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes the toxic and side effects in digestive system after chemotherapy (very low certainty).

• Chinese herbal medicines for induction of remission in advanced or late gastric cancer 2013 · Cochrane Headline outcomes only
  OR 1.13 [0.18, 7.24]
  3 studies · 153 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes the toxic and side effects of leukopenia after chemotherapy (very low certainty).

• Chinese herbal medicines for induction of remission in advanced or late gastric cancer 2013 · Cochrane Headline outcomes only
  OR 0.37 [0.18, 0.74]
  3 studies · 153 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes the rate of complete remission and partly remission (Copy) (very low certainty).

• Chinese herbal medicines for induction of remission in advanced or late gastric cancer 2013 · Cochrane Headline outcomes only
  OR 1.48 [1.01, 2.17]
  7 studies · 448 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes the toxic and side effects of leukopenia after chemotherapy(no… (very low certainty).

• Chinese herbal medicines for induction of remission in advanced or late gastric cancer 2013 · Cochrane Headline outcomes only
  OR 0.32 [0.21, 0.5]
  6 studies · 388 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes the rate of complete remission and partly remission(no special data… (very low certainty).

• Chinese herbal medicines for induction of remission in advanced or late gastric cancer 2013 · Cochrane Headline outcomes only
  OR 1.51 [0.94, 2.41]
  5 studies · 287 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes the toxic and side effects in digestive system after chemotherapy (very low certainty).

• Chinese herbal medicines for induction of remission in advanced or late gastric cancer 2013 · Cochrane Headline outcomes only
  OR 0.33 [0.2, 0.54]
  6 studies · 354 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes the toxic and side effects of leukopenia after chemotherapy(no… (very low certainty).

• Chinese herbal medicines for induction of remission in advanced or late gastric cancer 2013 · Cochrane Headline outcomes only
  OR 0.43 [0.23, 0.8]
  4 studies · 242 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes the rate of complete remission and partly remission(no special data… (very low certainty).

• Chinese herbal medicines for induction of remission in advanced or late gastric cancer 2013 · Cochrane Headline outcomes only
  OR 1.22 [0.83, 1.79]
  6 studies · 423 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes the toxic and side effects in digestive system after chemotherapy(no… (very low certainty).

• Chinese herbal medicines for induction of remission in advanced or late gastric cancer 2013 · Cochrane Headline outcomes only
  OR 0.42 [0.26, 0.69]
  4 studies · 302 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes the toxic and side effects of leukopenia after chemotherapy (very low certainty).

• Chinese herbal medicines for induction of remission in advanced or late gastric cancer 2013 · Cochrane Headline outcomes only
  OR 0.37 [0.25, 0.56]
  7 studies · 503 participants
  Very low

High vs non‐high (medium or low) dose regimen

High showed no clear difference in mortality compared with non‐high (medium or low) dose regimen (low certainty).

• Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding 2013 · Cochrane Headline outcomes only
  RR 0.85 [0.47, 1.54]
  12 studies · 1667 participants
  Low

High vs non‐high (medium or low) dose regimen

High showed no clear difference in rebleeding compared with non‐high (medium or low) dose regimen (low certainty).

• Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding 2013 · Cochrane Headline outcomes only
  RR 1.27 [0.96, 1.67]
  13 studies · 1716 participants
  Low

High vs non‐high (medium or low) dose regimen

High showed no clear difference in surgery compared with non‐high (medium or low) dose regimen (low certainty).

• Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding 2013 · Cochrane Headline outcomes only
  RR 1.33 [0.63, 2.77]
  9 studies · 1270 participants
  Low

High vs non‐high (medium or low) dose regimen

High showed no clear difference in further EHT compared with non‐high (medium or low) dose regimen (low certainty).

• Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding 2013 · Cochrane Headline outcomes only
  RR 1.39 [0.88, 2.18]
  6 studies · 902 participants
  Low

High vs non‐high (medium or low) dose regimen

• Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding 2013 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 1069 participants
  Moderate

High vs non‐high (medium or low) dose regimen

• Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding 2013 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 1069 participants
  Moderate

Perioperative chemotherapy vs primary surgery

Perioperative chemotherapy leads to lower overall survival among all patients compared with primary surgery (high certainty).

• Perioperative chemo(radio)therapy versus primary surgery for resectable adenocarcinoma of the stomach,… 2013 · Cochrane Headline outcomes only
  HR 0.81 [0.73, 0.89]
  14 studies · 2422 participants
  High

Perioperative chemotherapy vs primary surgery

Perioperative chemotherapy showed no clear difference in presence of tumor‐free resection margin compared with primary surgery (moderate certainty).

• Perioperative chemo(radio)therapy versus primary surgery for resectable adenocarcinoma of the stomach,… 2013 · Cochrane Headline outcomes only
  OR 1.42 [0.97, 2.06]
  10 studies · 1665 participants
  Moderate

Perioperative chemotherapy vs primary surgery

Perioperative chemotherapy probably leads to higher tumor stage at resection (T0 to T2 vs T3 to T4) compared with primary surgery (moderate certainty).

• Perioperative chemo(radio)therapy versus primary surgery for resectable adenocarcinoma of the stomach,… 2013 · Cochrane Headline outcomes only
  OR 1.53 [1.02, 2.31]
  8 studies · 1410 participants
  Moderate