Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,860 questions · 64,864 findings · 4,913 reviews · Headline outcomes only

No studies found 13,869 · 21.4%GRADE not reported 3,491 · 5.4%Very low 16,300 · 25.1%Low 17,338 · 26.7%Moderate 10,900 · 16.8%High 2,966 · 4.6%

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Lutein with or without zeaxanthin vs placebo

Progression to late AMD (neovascular AMD, geographic atrophy or both) · people with AMD

Lutein with or without zeaxanthin showed no clear difference in progression to late AMD (neovascular AMD, geographic atrophy, or both) compared with placebo (low certainty).

1 finding from 1 review

Summary of findings table ‐ Planned hospital birth vs Planned home birth

Baby not breastfed · Pregnant women at low risk of complications

It is very uncertain whether summary of findings table ‐ Planned hospital birth changes baby not breastfed compared with planned home birth (very low certainty).

1 finding from 1 review

Antibiotics vs placebo

Treatment incompletion (RR < 1 favored) · Participants with acute bacterial conjunctivitis

Antibiotics probably leads to lower treatment incompletion (RR < 1 favored) compared with placebo (moderate certainty).

1 finding from 1 review