Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,119 questions · 2,206 findings · 117 reviews · Common Mental Disorders

No studies found 387 · 17.5%GRADE not reported 111 · 5%Very low 635 · 28.8%Low 568 · 25.7%Moderate 449 · 20.4%High 56 · 2.5%

COMPARISON 1. ARIPIPRAZOLE vs other drugs

≥ 50% decrease in total YMRS from baseline at three weeks Young Mania Rating Scale (as above) · patients with an acute manic or mixed episode

Aripiprazole showed no clear difference in ≥ 50% decrease in YMRS from baseline at week three Young Mania… compared with other drug treatment (moderate certainty).

1 finding from 1 review

COMPARISON 1. ARIPIPRAZOLE vs other drugs

Numbers completing the trial (at end of week three) Number of participants · patients with an acute manic or mixed episode

Aripiprazole may leads to higher numbers completing the trial (at end of week three) Number of… compared with other drug treatment (low certainty).

1 finding from 1 review