Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,510 questions · 2,653 findings · 194 reviews · Gynaecology and Fertility

No studies found 531 · 20%GRADE not reported 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%

Anterior prolapse repair: native tissue vs polypropylene mesh

Repeat surgery ‐ surgery for prolapse, SUI, or mesh exposure review 1 to 3 years · women with anterior compartment pelvic organ prolapse

Anterior prolapse repair: native tissue probably leads to lower repeat surgery for prolapse, SUI or mesh exposure (1‐3 years) compared with polypropylene mesh (moderate certainty).

1 finding from 1 review

Anterior prolapse repair: native tissue vs absorbable mesh

Repeat surgery for prolapse (stage 2 or greater) at 2 years · women with anterior compartment pelvic organ prolapse

It is very uncertain whether anterior prolapse repair: native tissue changes repeat surgery for prolapse (stage 2 or greater) at 2 years compared with absorbable mesh (very low certainty).

1 finding from 1 review

Anterior prolapse repair: native tissue vs absorbable mesh

Recurrent anterior compartment prolapse (3 months to 2 years) · women with anterior compartment pelvic organ prolapse

Anterior prolapse repair: native tissue probably leads to higher recurrent anterior compartment prolapse (3 months to 2 years) compared with absorbable mesh (moderate certainty).

1 finding from 1 review

Anterior prolapse repair: native tissue vs biological graft

Recurrent anterior compartment prolapse (1‐2 years) · women with anterior compartment pelvic organ prolapse

Anterior prolapse repair: native tissue probably leads to higher recurrent anterior compartment prolapse (1‐2 years) compared with biological graft (moderate certainty).

1 finding from 1 review

Anterior prolapse repair: native tissue vs polypropylene mesh

Repeat surgery for stress urinary incontinence (2 years) · women with anterior compartment pelvic organ prolapse

Anterior prolapse repair: native tissue showed no clear difference in repeat surgery for stress urinary incontinence (1‐2 years) compared with polypropylene mesh (low certainty).

1 finding from 1 review

Anterior prolapse repair: native tissue vs polypropylene mesh

Recurrent anterior compartment prolapse (1‐3 years) · women with anterior compartment pelvic organ prolapse

Anterior prolapse repair: native tissue may leads to higher recurrent anterior compartment prolapse (1‐3 years) compared with polypropylene mesh (low certainty).

1 finding from 1 review

Day 3 vs Day 2 embryo transfer following IVF or ICSI

Live birth rate per woman · Women undergoing in vitro fertilisation or intracytoplasmic sperm injection

It is very uncertain whether day 3 changes live birth rate per woman compared with day 2 embryo transfer following IVF or ICSI (very low certainty).

1 finding from 1 review

Day 3 vs Day 2 embryo transfer following IVF or ICSI

Ongoing pregnancy · Women undergoing in vitro fertilisation or intracytoplasmic sperm injection

It is very uncertain whether day 3 changes ongoing pregnancy rate per woman compared with day 2 embryo transfer following IVF or ICSI (very low certainty).

1 finding from 1 review

Day 3 vs Day 2 embryo transfer following IVF or ICSI

Clinical pregnancy rate · Women undergoing in vitro fertilisation or intracytoplasmic sperm injection

It is very uncertain whether day 3 changes clinical pregnancy rate per woman compared with day 2 embryo transfer following IVF or ICSI (very low certainty).

1 finding from 1 review

Day 3 vs Day 2 embryo transfer following IVF or ICSI

Multiple pregnancy rate · Women undergoing in vitro fertilisation or intracytoplasmic sperm injection

Day 3 showed no clear difference in multiple pregnancy rate per woman compared with day 2 embryo transfer following IVF or ICSI (moderate certainty).

1 finding from 1 review

Day 3 vs Day 2 embryo transfer following IVF or ICSI

Miscarriage · Women undergoing in vitro fertilisation or intracytoplasmic sperm injection

Day 3 showed no clear difference in miscarriage rate per woman compared with day 2 embryo transfer following IVF or ICSI (moderate certainty).

1 finding from 1 review