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Evidence found and GRADE certainty

962 questions · 1,000 findings · 69 reviews · Urology

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No studies found 196 · 19.6%GRADE not reported 33 · 3.3%Very low 198 · 19.8%Low 354 · 35.4%Moderate 206 · 20.6%High 13 · 1.3%

NBI + WLC TURBT vs WLC TURBT

Time to recurrence · transurethral resection of bladder tumors in people with suspected or diagnosed non‐muscle invasive bladder cancer

NBI + WLC TURBT may leads to lower time to disease recurrence compared with WLC TURBT (low certainty).

1 finding from 1 review

NBI + WLC TURBT vs WLC TURBT

Clavien‐Dindo grade ≥ 3 complications · transurethral resection of bladder tumors in people with suspected or diagnosed non‐muscle invasive bladder cancer

NBI + WLC TURBT showed no clear difference in major adverse event (Clavien‐Dindo grade III, IV, and V) compared with WLC TURBT (low certainty).

1 finding from 1 review

NBI + WLC TURBT vs WLC TURBT

Clavien‐Dindo grade ≤ 2 complications8 · transurethral resection of bladder tumors in people with suspected or diagnosed non‐muscle invasive bladder cancer

NBI + WLC TURBT showed no clear difference in minor adverse event (Clavien‐Dindo grade I and II) compared with WLC TURBT (low certainty).

1 finding from 1 review

Transurethral microwave thermotherapy vs sham

Retreatment Participants requiring additional procedures or surgery · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Transurethral microwave thermotherapy may leads to lower retreatment Participants requiring additional procedures or surgery compared with sham treatment (low certainty).

1 finding from 1 review

Transurethral microwave thermotherapy vs transurethral resection of the prostate

Major adverse events · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Transurethral microwave thermotherapy probably leads to lower major adverse events compared with transurethral resection of the prostate (moderate certainty).

1 finding from 1 review

Transurethral microwave thermotherapy vs transurethral resection of the prostate

Retreatment Participants requiring additional procedures or surgery · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Transurethral microwave thermotherapy probably leads to higher retreatment Participants requiring additional procedures or surgery compared with transurethral resection of the prostate (moderate certainty).

1 finding from 1 review

Transurethral microwave thermotherapy vs transurethral resection of the prostate

Erectile function · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Transurethral microwave thermotherapy showed no clear difference in erectile function (sexually‐active men only) compared with transurethral resection of the prostate (low certainty).

1 finding from 1 review

Transurethral microwave thermotherapy vs transurethral resection of the prostate

Ejaculatory function · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Transurethral microwave thermotherapy may leads to lower ejaculatory function (sexually‐active men only) compared with transurethral resection of the prostate (low certainty).

1 finding from 1 review

Gemcitabine vs mitomycin

Grade III–V adverse events (local adverse events which result in delay intravesical treatment were regarded as Grade III–V complications) · patients with non‐muscle invasive bladder cancer

It is very uncertain whether gemcitabine changes grade III–V adverse events (local adverse events which result in… compared with mitomycin (very low certainty).

1 finding from 1 review