Gemcitabine vs mitomycin: Grade III–V adverse events (local adverse events which result in delay intravesical treatment were regarded as Grade III–V complications)
It is very uncertain whether gemcitabine changes grade III–V adverse events (local adverse events which result in… compared with mitomycin (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Gemcitabine vs mitomycin Grade III–V adverse events (local adverse events which result in delay intravesical treatment were regarded as Grade III–V complications) · participants with non‐muscle invasive bladder cancer1 (93 men, 16 women)Country: Italy It is very uncertain whether gemcitabine changes grade III–V adverse events (local adverse events which result in… compared with mitomycin (very low certainty). Intravesical gemcitabine for non‐muscle invasive bladder cancer (2021) · Cochrane Headline outcomes only | RR 0.51 [0.13, 1.93] | 1 study · 109 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Intravesical gemcitabine for non‐muscle invasive bladder cancer 2021 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.