Findings

What do systematic reviews say?

266 questions · 274 findings · 25 reviews · Movement Disorders

Sort:Best matchNewestHighest certainty Download CSV

No studies found 13 · 4.7%GRADE not reported 7 · 2.6%Very low 66 · 24.1%Low 66 · 24.1%Moderate 87 · 31.8%High 35 · 12.8%

Intervention not reported

Adverse effects of benztropine

1 finding from 1 review

Interventions for drooling in children with cerebral palsy 2012 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

Adverse effects of glycopyrrolate

1 finding from 1 review

Interventions for drooling in children with cerebral palsy 2012 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

Non‐compliance with intervention

1 finding from 1 review

Interventions for drooling in children with cerebral palsy 2012 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Whole body vibration vs an active physical therapy (short‐term effects)

Balance ( · patients with neurodegenerative disease

1 finding from 1 review

Whole‐body vibration training for patients with neurodegenerative disease 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 45 participants
Low

Whole body vibration vs an active physical therapy (short‐term effects)

Gait Timed Up and Go test · patients with neurodegenerative disease

1 finding from 1 review

Whole‐body vibration training for patients with neurodegenerative disease 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 45 participants
Low

Whole body vibration vs an active physical therapy (long‐term effects)

Balance ( · patients with neurodegenerative disease

1 finding from 1 review

Whole‐body vibration training for patients with neurodegenerative disease 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 42 participants
Very low

Whole body vibration vs an active physical therapy (long‐term effects)

Gait Time Up and Go test and Stand‐walk‐sit test · patients with neurodegenerative disease

1 finding from 1 review

Whole‐body vibration training for patients with neurodegenerative disease 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 42 participants
Very low

Whole body vibration vs an active physical therapy (long‐term effects)

UPDRS III UPDRS scale (motor score). Scale from: 0 to 56. · patients with neurodegenerative disease

1 finding from 1 review

Whole‐body vibration training for patients with neurodegenerative disease 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 42 participants
Very low

Summary of findings: levodopa vs placebo

Severity of symptoms (rating from 0 = not present to 10 = severe) · patients with restless legs syndrome

1 finding from 1 review

Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 48 participants
Moderate

Summary of findings: levodopa vs other dopamine agonists

Total sleep time, next night; · patients with restless legs syndrome

1 finding from 1 review

Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 11 participants
Very low

Summary of findings: levodopa vs other dopamine agonists

Adverse effects (drop‐outs due to adverse effects4) · patients with restless legs syndrome

Summary of findings: levodopa probably leads to lower number of drop outs due to adverse events compared with other dopamine agonists (moderate certainty).

1 finding from 1 review

Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
OR 0.59
3 studies · 504 participants
Moderate

Summary of findings: levodopa vs other dopamine agonists

Clinical Global Impressions ‐ Improvement of condition (CGI‐I) Rating of 1 = very much improved to 7 = very much worse · patients with restless legs syndrome

1 finding from 1 review

Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 344 participants
Moderate

Summary of findings: levodopa vs other dopamine agonists

Quality of sleep · patients with restless legs syndrome

1 finding from 1 review

Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 344 participants
Low

Summary of findings: levodopa vs other dopamine agonists

QoL · patients with restless legs syndrome

1 finding from 1 review

Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 314 participants
Moderate

Summary of findings: levodopa vs placebo

Periodic limb movements in sleep (PLMS Index) PLMS per hour of sleep (8 trials) or time in bed (7 trials) · patients with restless legs syndrome

1 finding from 1 review

Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 91 participants
Moderate

Summary of findings: levodopa vs placebo

Total sleep time, next night; · patients with restless legs syndrome

1 finding from 1 review

Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 59 participants
Low

Summary of findings: levodopa vs placebo

Dropouts due to adverse events · patients with restless legs syndrome

Summary of findings: levodopa showed no clear difference in dropouts due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
OR 0.73 [0.05, 11.34]
6 studies · 109 participants
Moderate

Summary of findings: levodopa vs placebo

Clinical Global Impressions ‐ Improvement of condition (CGI‐I) Rating of 1 = very much improved to 7 = very much worse · patients with restless legs syndrome

1 finding from 1 review

Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 60 participants
Moderate

Summary of findings: levodopa vs placebo

Quality of sleep · patients with restless legs syndrome

1 finding from 1 review

Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 60 participants
Moderate

Summary of findings: levodopa vs placebo

Quality of life VAS on life satisfaction (0 to 50 = high) · patients with restless legs syndrome

1 finding from 1 review

Levodopa for the treatment of restless legs syndrome 2011 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 60 participants
Moderate