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What do systematic reviews say?

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Evidence found and GRADE certainty

3 questions · 3 findings · 3 reviews · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%

Gemcitabine vs Normal saline

Overall survival (absolute effect size estimates based on survival rate at 12 months) · patients with non‐muscle invasive bladder cancer

It is very uncertain whether gemcitabine changes time to death from any cause (absolute effect size estimates based… compared with saline (very low certainty).

1 finding from 1 review

Impact of extended vs standard lymph node dissection on overall survival among patients with urothelial cancer of the bladder

Overall survival (absolute effect size estimates based on survival rate at 24 months) · Partcipants with bladder cancer undergoing radical cystectomy (male n = 314, female n = 87; age (interquartile range) 59 to 74)Country:…

Impact of extended showed no clear difference in time to death from any cause (absolute effect size estimates based… compared with standard lymph node dissection on overall survival among patients… (low certainty).

1 finding from 1 review

Bacillus Calmette‐Guérin (BCG) vs mitomycin

Overall survival (absolute effect size estimates based on survival rate at 24 months)

Bacillus Calmette‐Guérin (BCG) showed no clear difference in time to death from any cause (absolute effect size estimates based… compared with mitomycin C (MMC) (low certainty).

1 finding from 1 review