What do systematic reviews say?

Orexin antagonists vs placebo

The review found no eligible studies for this question.

• Pharmacotherapies for sleep disturbances in dementia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Melatonin vs placebo

The review found no eligible studies for this question.

• Pharmacotherapies for sleep disturbances in dementia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Iron chelator vs placebo

The review found no eligible studies for this question.

• Iron chelators for acute stroke 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Sublingual immunotherapy vs control

The review found no eligible studies for this question.

• Sublingual immunotherapy for asthma 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Azelaic acid vs clindamycin

The review found no eligible studies for this question.

• Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Azelaic acid vs tretinoin

The review found no eligible studies for this question.

• Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Salicylic acid vs pyruvic acid

The review found no eligible studies for this question.

• Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Nicotinamide vs clindamycin

The review found no eligible studies for this question.

• Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Nicotinamide vs erythromycin

The review found no eligible studies for this question.

• Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Glycolic acid (alpha‐hydroxy acid) vs salicylic‐mandelic acid

The review found no eligible studies for this question.

• Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Azelaic acid vs benzoyl peroxide

The review found no eligible studies for this question.

• Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

220 mg zinc sulphate supplement containing 50 mg elemental zinc vs placebo

The review found no eligible studies for this question.

• Nutritional interventions for treating foot ulcers in people with diabetes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

250 mg magnesium oxide supplement vs placebo

The review found no eligible studies for this question.

• Nutritional interventions for treating foot ulcers in people with diabetes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oral nutritional supplements vs placebo

The review found no eligible studies for this question.

• Nutritional interventions for treating foot ulcers in people with diabetes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

1000 mg/day omega‐3 fatty acid from flaxseed oil supplement vs placebo

The review found no eligible studies for this question.

• Nutritional interventions for treating foot ulcers in people with diabetes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

150,000 IU of vitamin D vs 300,000 IU of vitamin D

The review found no eligible studies for this question.

• Nutritional interventions for treating foot ulcers in people with diabetes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Magnesium and vitamin E co‐supplementation vs placebo

The review found no eligible studies for this question.

• Nutritional interventions for treating foot ulcers in people with diabetes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Vitamin D vs placebo

The review found no eligible studies for this question.

• Nutritional interventions for treating foot ulcers in people with diabetes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement vs placebo

It is very uncertain whether arginine, glutamine and β‐hydroxy‐β‐methylbutyrate supplement changes quality of life compared with placebo (very low certainty).

• Nutritional interventions for treating foot ulcers in people with diabetes 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 270 participants
  Very low

Daily conventionally fractionated radiotherapy vs supportive care

• External beam radiation dose escalation for high grade glioma 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 81 participants
  GRADE not reported