Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,241 questions · 3,336 findings · 1,340 reviews

No studies found 1,581 · 47.4%GRADE not reported 352 · 10.6%Very low 512 · 15.3%Low 509 · 15.3%Moderate 316 · 9.5%High 66 · 2%

Long‐acting beta2‐agonist plus tiotropium vs tiotropium

Quality of life SGRQ responder analysis at 6 months · addition to tiotropium versus either tiotropium or LABA alone for chronic obstructive pulmonary disease

Long‐acting beta2‐agonist plus tiotropium probably leads to higher quality of life SGRQ responder analysis at 6 months compared with tiotropium alone (moderate certainty).

1 finding from 1 review

Long‐acting beta2‐agonist plus tiotropium vs long‐acting beta2‐agonist alone

Quality of life SGRQ responder analysis at 6 months · addition to tiotropium versus either tiotropium or LABA alone for chronic obstructive pulmonary disease

Long‐acting beta2‐agonist plus tiotropium probably leads to higher quality of life SGRQ responder analysis at 6 months compared with long‐acting beta2‐agonist alone (moderate certainty).

1 finding from 1 review

CBT vs TAU

Quality of life (Higher scores indicate improvement) · chronic pain (excluding headache) in adults
2 findings from 1 review

CBT vs active control

Quality of life (Higher scores indicate improvement) · chronic pain (excluding headache) in adults
2 findings from 1 review

Intervention not reported

General health‐related quality of life [GHQ‐28, IES, · women with primary breast cancer

It is very uncertain whether the intervention changes general health‐related quality of life [GHQ‐28, IES, (very low certainty).

1 finding from 1 review