Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews · Neonatal

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Meropenem vs usual care

Necrotising enterocolitis maximum · newborns with late‐onset sepsis

It is very uncertain whether meropenem changes necrotising enterocolitis maximum compared with standard care (very low certainty).

1 finding from 1 review

Antibiotic regimens for late‐onset neonatal sepsis 2021 · Cochrane Headline outcomes only
RR 0.68 [0.33, 1.42]
1 study · 271 participants
Very low

Vancomycin plus gentamicin vs vancomycin plus aztreonam

Necrotising enterocolitis maximum · newborns with late‐onset sepsis

It is very uncertain whether vancomycin plus gentamicin changes necrotising enterocolitis maximum compared with vancomycin plus aztreonam (very low certainty).

1 finding from 1 review

Antibiotic regimens for late‐onset neonatal sepsis 2021 · Cochrane Headline outcomes only
RR 12.69 [0.74, 218.09]
1 study · 81 participants
Very low

Ampicillin plus gentamicin vs penicillin plus gentamicin

Necrotising enterocolitis maximum · neonates with early‐onset sepsis

It is very uncertain whether ampicillin plus gentamicin changes necrotising enterocolitis maximum compared with penicillin plus gentamicin (very low certainty).

1 finding from 1 review

Antibiotic regimens for early‐onset neonatal sepsis 2021 · Cochrane Headline outcomes only
RR 1.24 [0.5, 3.05]
1 study · 283 participants
Very low