Findings

What do systematic reviews say?

8 questions · 8 findings · 3 reviews · Airways

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 12.5%Low 3 · 37.5%Moderate 4 · 50%High 0 · 0%

Mortality at end of · patients with chronic obstructive pulmonary disease

Endobronchial coils showed no clear difference in mortality at end of compared with control (moderate certainty).

1 finding from 1 review

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
OR 1.49 [0.67, 3.29]
3 studies · 461 participants
Moderate

Mortality at end of · patients with chronic obstructive pulmonary disease

AeriSeal showed no clear difference in mortality at end of compared with control (low certainty).

1 finding from 1 review

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
OR 2.9 [0.14, 62.15]
1 study · 95 participants
Low

Mortality at end of · patients with chronic obstructive pulmonary disease

Endobronchial valves showed no clear difference in mortality at end of compared with control (moderate certainty).

1 finding from 1 review

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
OR 1.07 [0.47, 2.43]
5 studies · 703 participants
Moderate

Mortality at end of · patients with chronic obstructive pulmonary disease

Intrabronchial valves showed no clear difference in mortality at end of compared with control (moderate certainty).

1 finding from 1 review

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
OR 4.95 [0.85, 28.94]
2 studies · 350 participants
Moderate

Mortality at end of · patients with chronic obstructive pulmonary disease

Vapour ablation showed no clear difference in mortality at end of compared with control (low certainty).

1 finding from 1 review

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
OR 2.82 [0.13, 61.06]
1 study · 69 participants
Low

Mortality at end of · patients with chronic obstructive pulmonary disease

Airway bypass stents showed no clear difference in mortality at end of compared with control (moderate certainty).

1 finding from 1 review

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
OR 0.76 [0.21, 2.77]
1 study · 350 participants
Moderate

Mortality (to end of · post‐exacerbation COPD

Pulmonary rehabilitation showed no clear difference in mortality (to end of compared with usual care (low certainty).

1 finding from 1 review

Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease 2016 · Cochrane Headline outcomes only
OR 0.68 [0.28, 1.67]
6 studies · 670 participants
Low

All‐cause mortality 60 weeks (end of study) · patients with chronic obstructive pulmonary disease

It is very uncertain whether macrolide+tetracycline changes all‐cause mortality 60 weeks (end of study) compared with macrolide (very low certainty).

1 finding from 1 review

Head‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
OR 1.63 [0.38, 7.02]
1 study · 198 participants
Very low