What do systematic reviews say?

Intervention not reported

It is very uncertain whether the intervention changes health‐related quality of life (Change in CRQ Emotional Function) CRQ (very low certainty).

• Exercise training to improve exercise capacity and quality of life in people with non‐malignant dust‐related… 2015 · Cochrane Headline outcomes only
  MD 2.61 [0.74, 4.49]
  2 studies · 39 participants
  Very low

Anti‐IL13 or anti‐IL4 agents vs placebo

• Anti‐interleukin‐13 and anti‐interleukin‐4 agents versus placebo, anti‐interleukin‐5 or anti‐immunoglobulin‐E agents,… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 4960 participants
  High

Metformin vs insulin

• Metformin monotherapy for adults with type 2 diabetes mellitus 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 91 participants
  Very low

Mepolizumab intravenous (IV) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 369 participants
  High

Reslizumab intravenous (IV) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1164 participants
  High

Reslizumab subcutaneous (SC) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 464 participants
  High

Benralizumab subcutaneous (SC) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1541 participants
  High

Exercise vs control group

• Exercise training undertaken by people within 12 months of lung resection for non‐small cell lung cancer 2019 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 208 participants
  Low

ICS dose reduction vs no change

• Stepping down the dose of inhaled corticosteroids for adults with asthma 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 554 participants
  Very low

Reslizumab intravenous (IV) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1652 participants
  High

Reslizumab subcutaneous (SC) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 464 participants
  High

Mepolizumab subcutaneous (SC) vs placebo

• Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1231 participants
  High

Yoga vs no therapy

• Yoga for improving health‐related quality of life, mental health and cancer‐related symptoms in women diagnosed with… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 675 participants
  Moderate

Yoga vs psychosocial/educational interventions

• Yoga for improving health‐related quality of life, mental health and cancer‐related symptoms in women diagnosed with… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 153 participants
  Very low

Treatment informed by feedback of patient reported outcome measures vs treatment

• Routine use of patient reported outcome measures (PROMs) for improving treatment of common mental health disorders in… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 583 participants
  Moderate

Closing wedge high tibial osteotomy (CW‐HTO) vs unicompartmental knee arthroplasty

The review found no eligible studies for this question.

• Osteotomy for treating knee osteoarthritis 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Exercise vs control group

• Exercise training undertaken by people within 12 months of lung resection for non‐small cell lung cancer 2019 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 208 participants
  Low

Yoga vs no therapy

• Yoga for improving health‐related quality of life, mental health and cancer‐related symptoms in women diagnosed with… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 146 participants
  Low

Aerobic exercise vs control

• Aerobic exercise training for adults with fibromyalgia 2017 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 372 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in health‐related quality of life scores, measured by SF‐36 (range 0 to… (low certainty).

• Surgical versus medical interventions for chronic rhinosinusitis with nasal polyps 2014 · Cochrane Headline outcomes only
  MD 0.6
  1 study · 95 participants
  Low