Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews · Common Mental Disorders

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 66.7%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Escitalopram vs placebo

Dropouts due to adverse events · adults experiencing acute traumatic stress symptoms

1 finding from 1 review

Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Very low

Hydrocortisone vs placebo

Dropouts due to adverse events · adults experiencing acute traumatic stress symptoms

Hydrocortisone showed no clear difference in dropouts due to adverse events at 3 months compared with placebo (low certainty).

1 finding from 1 review

Early pharmacological interventions for prevention of post‐traumatic stress disorder (PTSD) in individuals… 2024 · Cochrane Headline outcomes only
RR 3.19 [0.13, 75.43]
2 studies · 182 participants
Low

Comparison 13: SSRIs vs placebo

Dropouts due to adverse events · adults with SAnD

It is very uncertain whether comparison 13: SSRIs changes dropouts due to adverse events (long term) Post‐treatment: 1‐4 months compared with placebo (very low certainty).

1 finding from 1 review

Pharmacotherapy for social anxiety disorder (SAnD) 2017 · Cochrane Headline outcomes only
RR 1.17 [0.43, 3.18]
3 studies · 1274 participants
Very low