Findings

What do systematic reviews say?

5 questions · 5 findings · 4 reviews · Heart

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 20%Low 2 · 40%Moderate 2 · 40%High 0 · 0%

Cardiovascular mortality · patients with coronary heart disease

Antibiotics showed no clear difference in cardiovascular mortality at maximum compared with placebo or no intervention (moderate certainty).

1 finding from 1 review

Antibiotics for secondary prevention of coronary heart disease 2021 · Cochrane Headline outcomes only
RR 1.11 [0.98, 1.25]
2 studies · 4674 participants
Moderate

Cardiovascular mortality at maximum · patients without heart failure

The intervention may leads to lower cardiovascular mortality at maximum (low certainty).

1 finding from 1 review

Beta‐blockers in patients without heart failure after myocardial infarction 2021 · Cochrane Headline outcomes only
RR 0.73 [0.61, 0.88]
19 studies · 21763 participants
Low

Cardiovascular mortality · patients with suspected or diagnosed myocardial infarction

Beta‐blockers probably leads to lower cardiovascular mortality at maximum compared with placebo or no intervention (moderate certainty).

1 finding from 1 review

Beta‐blockers for suspected or diagnosed acute myocardial infarction 2019 · Cochrane Headline outcomes only
RR 0.9 [0.83, 0.98]
14 studies · 22457 participants
Moderate

Cardiovascular mortality · patients with acute coronary syndrome

It is very uncertain whether drug‐eluting stents changes cardiovascular mortality at maximum compared with bare‐metal stents (very low certainty).

1 finding from 1 review

Drug‐eluting stents versus bare‐metal stents for acute coronary syndrome 2017 · Cochrane Headline outcomes only
RR 0.91 [0.76, 1.09]
14 studies · 9248 participants
Very low

Major cardiovascular events (cardiovascular mortality or non‐fatal myocardial infarction) at maximum · patients without heart failure

The intervention may leads to lower major cardiovascular events (cardiovascular mortality or non‐fatal… (low certainty).

1 finding from 1 review

Beta‐blockers in patients without heart failure after myocardial infarction 2021 · Cochrane Headline outcomes only
RR 0.72 [0.62, 0.83]
15 studies · 14994 participants
Low