Nausea · adults with schizophrenia
Noradrenaline reuptake inhibitors showed no clear difference in adverse effects: Nausea ‐ short term (2 to 12 weeks) compared with placebo (low certainty).
1 finding from 1 review
Number with treatment stopped due to adverse effects · Adults or adolescents with opioid dependence
Buprenorphine showed no clear difference in number with treatment stopped due to adverse effects compared with alpha2‐adrenergic agonists (low certainty).
1 finding from 1 review
Adverse effects: unspecified extrapyramidal symptoms · schizophrenia
CHLORPROMAZINE LOW DOSE (≤ 400 mg/day) probably leads to lower adverse effects: unspecified extrapyramidal symptoms compared with HIGH DOSE (> 800 mg/day ‐ all medium term) (moderate certainty).
1 finding from 1 review
Adverse effects: Specific ‐ dystonia during 24 hours · psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes adverse effects: Specific ‐ dystonia during 24 hours compared with OTHER ANTIPSYCHOTIC: e. OLANZAPINE (very low certainty).
1 finding from 1 review
Adverse effects: Specific ‐ dystonia during 24 hours · patients with psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes adverse effects: Specific ‐ dystonia within 24 hours compared with PLACEBO/NIL (very low certainty).
1 finding from 1 review
Adverse effects: Specific ‐ dystonia between 0‐3 days (IM phase) · psychosis‐induced aggression or agitation
It is very uncertain whether HALOPERIDOL changes adverse effects: Specific ‐ dystonia during 72 hours compared with OTHER ANTIPSYCHOTIC: j. ZIPRASIDONE (very low certainty).
1 finding from 1 review
Adverse effects: SPRM‐associated endometrial changes · uterine fibroids
SPRM probably leads to higher adverse effects: SPRM‐associated endometrial changes compared with leuprolide acetate (moderate certainty).
1 finding from 1 review
Adverse effects: SPRM‐associated endometrial changes · women with uterine fibroids
SPRM may leads to higher adverse effects: SPRM‐associated endometrial changes compared with placebo (low certainty).
1 finding from 1 review
Safety of the intervention (adverse effects) · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
Safety of the intervention (adverse effects) · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
Safety of the intervention (adverse effects) · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
Safety of the intervention (adverse effects) · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
SoF (topical interventions vs placebo), grouped comment spanning all four listed outcomes (verbatim): "5 placebo-controlled trials evaluated topical interventions (sucralfate suspension (2 trials), interferon-alpha (2…
Studies not reported
GRADE not reported
Safety of the intervention (adverse effects) · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
Hamuryudan 1998: significant adverse effects including severe sedation, polyneuropathy, loss of libido, and weight gain; a greater number of adverse events was seen for the higher (300 mg) dose; 4 patients withdrew due…
1 study · 101 participants
GRADE not reported
Adverse effects of endoscopy therapy Adverse effects · patients with high‐risk bleeding ulcers
Epinephrine probably leads to higher adverse effects of endoscopy therapy Adverse effects compared with epinephrine and any second endoscopic method (moderate certainty).
1 finding from 1 review
Safety of the intervention (adverse effects) · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
Alpsoy 2002: high rate of adverse events including alopecia, leukopenia, and diarrhoea; 18 of 23 patients in the treatment arm experienced mild flu-like symptoms.
1 study · 50 participants
GRADE not reported
Adverse effects: acute severe visual acuity decrease · people with neovascular age‐related macular degeneration
Photodynamic therapy with verteporfin showed no clear difference in adverse effects: acute severe visual acuity decrease compared with photodynamic therapy with 5% dextrose (moderate certainty).
1 finding from 1 review
Adverse effects other than prolonged vaginal bleeding · postpartum people who desire a contraceptive implant for contraception
Immediate may leads to higher adverse effects other than prolonged vaginal bleeding compared with delayed postpartum insertion of contraceptive implants (low certainty).
1 finding from 1 review
Adverse effects (urethral trauma/bleeding/haematuria) · long‐term bladder management
Hydrophilic‐coated catheter probably leads to higher adverse effects (urethral trauma/bleeding/haematuria) compared with uncoated catheter (moderate certainty).
1 finding from 1 review
Adverse effects (urethral trauma/bleeding/haematuria) · long‐term bladder management
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects: toxic death (no definition provided) · children with cancer treated with platinum‐based therapy
Continuous platinum infusion showed no clear difference in adverse effects: toxic death (no definition provided) compared with bolus platinum infusion (low certainty).
1 finding from 1 review