Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

347 questions · 355 findings · 51 reviews

No studies found 135 · 38%GRADE not reported 45 · 12.7%Very low 90 · 25.4%Low 63 · 17.7%Moderate 15 · 4.2%High 7 · 2%

Systemic antibiotics without surgical intervention (with or without analgesics) vs Matched placebo without surgical intervention (with or without analgesics)

Outcome not reported · Adults with symptomatic apical periodontitis or acute apical abscess

The review found no eligible studies for this question.

1 finding from 1 review

Passive maxillary/obturating plate (worn until surgical closure of soft palate) vs No plate

Weight (kg) · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or other syndromes…

Passive maxillary/obturating plate (worn until surgical closure of… showed no clear difference in weight (kg) compared with no plate; GRADE not reported.

1 finding from 1 review

Passive maxillary/obturating plate (worn until surgical closure of soft palate) vs No plate

Head circumference (mm) · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or other syndromes…

Passive maxillary/obturating plate (worn until surgical closure of… showed no clear difference in head circumference (cm) compared with no plate; GRADE not reported.

1 finding from 1 review

Passive maxillary/obturating plate (worn until surgical closure of soft palate) vs No plate

Length (cm) · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or other syndromes…

Passive maxillary/obturating plate (worn until surgical closure of… showed no clear difference in length (cm) compared with no plate; GRADE not reported.

1 finding from 1 review

Medical or surgical intervention, or both, for gastro‐oesophageal reflux disease vs nil intervention, delayed intervention control, or placebo

Exacerbations: number of people experiencing moderate or severe exacerbations · treatment for asthma in adults and children with asthma and GORD

Medical or surgical intervention, or both, for gastro‐oesophageal… showed no clear difference in number of participants with moderate/severe acute exacerbations… compared with nil intervention, delayed intervention control, or placebo (low certainty).

1 finding from 1 review

Medical or surgical intervention, or both, for gastro‐oesophageal reflux disease vs nil intervention, delayed intervention control, or placebo

Lung function: FEV1 mL (change from baseline) · treatment for asthma in adults and children with asthma and GORD
1 finding from 1 review

Medical or surgical intervention, or both, for gastro‐oesophageal reflux disease vs nil intervention, delayed intervention control, or placebo

Use of "rescue" medications and emergency action plans: B2 use puffs per day Duration of treatment: range 14 weeks to 24 weeks · treatment for asthma in adults and children with asthma and GORD
1 finding from 1 review

Medical or surgical intervention, or both, for gastro‐oesophageal reflux disease vs nil intervention, delayed intervention control, or placebo

Healthcare utilisation ‐ not measured · treatment for asthma in adults and children with asthma and GORD

The review found no eligible studies for this question.

1 finding from 1 review

Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Undesirable outcomes associated with removal (alveolar osteitis/postoperative infection, nerve injury, damage to adjacent teeth, bleeding, osteonecrosis, inflammation/infection) · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth

The review found no eligible studies for this question.

1 finding from 1 review

Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Other pathological changes associated with retention (pericoronitis, root resorption, cyst formation, tumour formation, inflammation/infection) · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth

The review found no eligible studies for this question.

1 finding from 1 review

Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Arch length (dental arch dimensional change) · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth

Surgical removal (extraction) of asymptomatic disease-free impacted… may leads to lower arch length (dimensional changes in the dental arch) compared with retention (conservative management) of asymptomatic disease-free… (low certainty).

1 finding from 1 review

Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Little's irregularity index (dimensional changes in the dental arch) · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth

Surgical removal (extraction) of asymptomatic disease-free impacted… showed no clear difference in little's irregularity index (dimensional changes in the dental arch) compared with retention (conservative management) of asymptomatic disease-free… (low certainty).

1 finding from 1 review

Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Costs (days off work/study; direct costs of retention or removal) · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth

The review found no eligible studies for this question.

1 finding from 1 review

Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Health‐related quality of life · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth

The review found no eligible studies for this question.

1 finding from 1 review

Surgical removal (extraction) of asymptomatic disease-free impacted wisdom teeth vs Retention (conservative management) of asymptomatic disease-free impacted wisdom teeth

Intercanine width · Adolescents or adults with asymptomatic disease-free impacted wisdom teeth

Surgical removal (extraction) of asymptomatic disease-free impacted… showed no clear difference in intercanine width (dimensional changes in the dental arch) compared with retention (conservative management) of asymptomatic disease-free… (low certainty).

1 finding from 1 review