Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

557 questions · 600 findings · 75 reviews

No studies found 188 · 31.3%GRADE not reported 62 · 10.3%Very low 154 · 25.7%Low 122 · 20.3%Moderate 62 · 10.3%High 12 · 2%

Open surgery vs steroid injection

Participant global assessment of success Not measured · patients with trigger finger

The review found no eligible studies for this question.

1 finding from 1 review

Open surgery vs steroid injection

Recurrence · patients with trigger finger

Open surgery may leads to lower recurrence compared with steroid injection (low certainty).

1 finding from 1 review

Open surgery vs steroid injection

Adverse events (infection, tendon or pulley injury, flare, cutaneous discomfort, fat necrosis) · patients with trigger finger

Open surgery showed no clear difference in adverse events (infection, tendon or pulley injury, flare, cutaneous… compared with steroid injection (low certainty).

1 finding from 1 review

Open surgery vs steroid injection

Neurovascular injury · patients with trigger finger

Open surgery showed no clear difference in neurovascular injury compared with steroid injection (low certainty).

1 finding from 1 review

Open surgery vs ERCP

Retained stones after primary intervention · with common bile duct stones

Open surgery probably leads to lower retained stones after primary intervention compared with ERCP (moderate certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Adverse events · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes adverse events compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Surgery for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes surgery for recurrent or persistent disease compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review

Surgery vs preoperative pharmacological therapy and surgery

Non‐surgical therapy for recurrent or persistent diseaseRadiation therapy and/or pharmacologic therapy for recurrent or persistent disease · adults with growth‐hormone secreting pituitary adenomas

It is very uncertain whether surgery alone changes non‐surgical therapy for recurrent or persistent diseaseRadiation… compared with preoperative pharmacological therapy and surgery (very low certainty).

1 finding from 1 review

Surgery vs Pharmacological therapy

Health‐related quality of life Mean AcroQoL score (0‐100) · adults with growth‐hormone secreting pituitary adenomas

Surgery alone showed no clear difference in health‐related quality of life Mean AcroQoL score (0‐100) compared with pharmacological therapy alone (low certainty).

1 finding from 1 review