Findings

What do systematic reviews say?

4 questions · 4 findings · 2 reviews

No studies found 1 · 25%GRADE not reported 0 · 0%Very low 2 · 50%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

SAEs · psoriatic arthritis

Methotrexate showed no clear difference in serious adverse events (SAEs) assessed by number of events compared with placebo (low certainty).

1 finding from 1 review

Methotrexate for psoriatic arthritis 2019 · Cochrane Headline outcomes only
RR 0.26 [0.03, 2.26]
3 studies · 293 participants
Low

Serious adverse events (leflunomide) assessed by number of events · psoriatic arthritis

1 finding from 1 review

Methotrexate for psoriatic arthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 61 participants
Very low

Serious adverse events (ciclosporin A) assessed by number of events · psoriatic arthritis

1 finding from 1 review

Methotrexate for psoriatic arthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 35 participants
Very low

Serious adverse events (number of events) · people with primary biliary cholangitis

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for primary biliary cholangitis 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found