Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

164 questions · 176 findings · 17 reviews

No studies found 48 · 27.3%GRADE not reported 21 · 11.9%Very low 87 · 49.4%Low 16 · 9.1%Moderate 4 · 2.3%High 0 · 0%

Low‐level laser therapy vs placebo

Change in feeling of dryness · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

The review found no eligible studies for this question.

1 finding from 1 review

Low‐level laser therapy vs placebo

Adverse effects · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

The review found no eligible studies for this question.

1 finding from 1 review

Low‐level laser therapy vs placebo

Change in taste · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

The review found no eligible studies for this question.

1 finding from 1 review

Surgical removal of the lesion (surgical excision, laser surgery, cryotherapy) vs Placebo or no treatment

Outcome not reported · People with a diagnosis of oral leukoplakia

The review found no eligible studies for this question.

1 finding from 1 review
  • 'We did not identify any RCTs that compared surgical treatments with placebo or no treatment.' Three surgical RCTs were found (Chee 2013, Lopez-Jornet 2013, Schwarz 2005) but all excluded because they did not include a…
    Studies not reported
    No studies found

Anti‐vascular endothelial growth factor therapy combined with laser/cryotherapy vs conventional laser/cryotherapy

Structural outcome ‐ retinal detachment · preterm infants with type 1 ROP

Anti‐vascular endothelial growth factor therapy combined with… may leads to lower structural outcome ‐ retinal detachment (unit of analysis: eyes) compared with laser/cryotherapy (low certainty).

1 finding from 1 review

Anti‐vascular endothelial growth factor therapy combined with laser/cryotherapy vs conventional laser/cryotherapy

Local adverse effects ‐ perioperative retinal haemorrhages (unit of analysis: eyes) · preterm infants with type 1 ROP

It is very uncertain whether anti‐vascular endothelial growth factor therapy combined with… changes local adverse effects ‐ perioperative retinal haemorrhages (unit of… compared with laser/cryotherapy (very low certainty).

1 finding from 1 review

Anti‐vascular endothelial growth factor therapy combined with laser/cryotherapy vs conventional laser/cryotherapy

Recurrence of ROP by 55 weeks' PMA · preterm infants with type 1 ROP

Anti‐vascular endothelial growth factor therapy combined with… may leads to lower recurrence of ROP by 55 weeks' postmenstrual age compared with laser/cryotherapy (low certainty).

1 finding from 1 review

Low‐level laser therapy vs Placebo (sham) laser therapy

Patient-reported altered sensation (spontaneous or evoked: anaesthesia/paraesthesia/dysaesthesia/hyperalgesia/allodynia) · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

It is very uncertain whether low-level laser therapy (photon-plus GaAlAs diode laser; 70 mW… changes patient-reported altered sensation (spontaneous or evoked:… compared with placebo (sham) laser therapy (very low certainty).

2 findings from 1 review

Low‐level laser therapy vs Placebo (sham) laser therapy

Somatosensory evoked potentials · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Low‐level laser therapy vs Placebo (sham) laser therapy

Mechanosensory perception (load in grams to elicit sensation; Semmes Weinstein monofilaments) · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

Low-level laser therapy (photon-plus GaAlAs diode laser; 70 mW… led to higher mechanosensory perception (load in grams to elicit sensation; Semmes… compared with placebo (sham) laser therapy; GRADE not reported.

1 finding from 1 review