Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 1 · 20%Very low 0 · 0%Low 4 · 80%Moderate 0 · 0%High 0 · 0%

HALOPERIDOL + PROMETHAZINE vs OLANZAPINE

Adverse effects: Specific and serious adverse effect ‐ by 24 hours Central nervous system ‐ excessive sedation · people with psychosis‐induced aggression

HALOPERIDOL + PROMETHAZINE showed no clear difference in adverse effects: Specific and serious adverse effects by 24 hours… compared with ANTIPSYCHOTIC ‐ OLANZAPINE (low certainty).

1 finding from 1 review

HALOPERIDOL + PROMETHAZINE vs ANTIPSYCHOTIC & BENZODIAZEPINE ‐ HALOPERIDOL + MIDAZOLAM

Adverse effects: Specific and serious adverse effect ‐ by 24 hours Central nervous system ‐ excessive sedation · people with psychosis‐induced aggression

HALOPERIDOL + PROMETHAZINE may leads to lower adverse effects: Specific and serious adverse effect ‐ by 24 hours… compared with ANTIPSYCHOTIC & BENZODIAZEPINE ‐ HALOPERIDOL + MIDAZOLAM (low certainty).

1 finding from 1 review

HALOPERIDOL + PROMETHAZINE vs haloperidol

Adverse effects: Specific and serious adverse effects by 24 hours (not death) Central nervous system ‐ seizure · people with psychosis‐induced aggression

HALOPERIDOL + PROMETHAZINE showed no clear difference in adverse effects: Specific and serious adverse effects by 24 hours… compared with ANTIPSYCHOTIC ‐ HALOPERIDOL (low certainty).

1 finding from 1 review

HALOPERIDOL + PROMETHAZINE vs ZIPRASIDONE

Adverse effects: Specific and serious adverse effect ‐ by 24 hours Central nervous system ‐ excessive sedation · people with psychosis‐induced aggression

HALOPERIDOL + PROMETHAZINE showed no clear difference in adverse effects: Specific and serious adverse effect ‐ by 24 hours… compared with ANTIPSYCHOTIC ‐ ZIPRASIDONE (low certainty).

1 finding from 1 review