Congenital abnormality · pregnant women
Topical corticosteroids may leads to lower congenital abnormality compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.82
9433 participants
Low
Orofacial cleft · pregnant women
Topical corticosteroids may leads to higher orofacial cleft compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 1.12
40605 participants
Low
Low birthweight · pregnant women
It is very uncertain whether topical corticosteroids changes low birth weight compared with no topical corticosteroids (very low certainty).
1 finding from 1 review
RR 1.08
59419 participants
Very low
Preterm birth · pregnant women
Topical corticosteroids may leads to lower preterm delivery compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.93
59419 participants
Low
Foetal death · pregnant women
It is very uncertain whether topical corticosteroids changes foetal death compared with no topical corticosteroids (very low certainty).
1 finding from 1 review
RR 1.02
63885 participants
Very low
Low Apgar score · pregnant women
Topical corticosteroids may leads to lower low Apgar score compared with no topical corticosteroids (low certainty).
1 finding from 1 review
RR 0.84
9220 participants
Low
Duration to heal oral ulcerations after initiation of treatment · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
The review found no eligible studies for this question.
1 finding from 1 review
Healing of ulceration · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
The review found no eligible studies for this question.
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects of long‐term use of available topical agents · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
The review found no eligible studies for this question.
1 finding from 1 review
Incidence and recurrence after healing of ulcers · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers
The review found no eligible studies for this question.
1 finding from 1 review
Worse or unimproved within 5 weeks from randomisation · multiple sclerosis patients with acute exacerbations
Corticosteroids or ACTH probably leads to lower worse or unimproved within 5 weeks from randomisation compared with placebo (moderate certainty).
1 finding from 1 review
Mean disability (EDSS) score—at 1 week after randomisation · multiple sclerosis patients with acute exacerbations
Corticosteroids or ACTH showed no clear difference in mean disability (EDSS) score—at 1 week after randomisation compared with placebo (moderate certainty).
1 finding from 1 review
Participants with new exacerbations during · multiple sclerosis patients with acute exacerbations
It is very uncertain whether corticosteroids or ACTH changes participants with new exacerbations during compared with placebo (very low certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with radicular low back pain (not due to spinal stenosis)
1 finding from 1 review
Function (continuous) RDQ‐18 (scale 0–18) · people with non‐radicular low back pain
1 finding from 1 review
Function (dichotomous) RDQ‐18 = 0 · people with non‐radicular low back pain
Systemic corticosteroids showed no clear difference in function (dichotomous) RDQ‐18 = 0 compared with placebo (low certainty).
1 finding from 1 review
Surgery Number of participants who underwent surgery · people with non‐radicular low back pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participants who experienced a serious adverse event · people with non‐radicular low back pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participants who experienced any adverse event Adverse event regardless of severity · people with non‐radicular low back pain
Systemic corticosteroids may leads to lower participants who experienced any adverse event Adverse event… compared with placebo (low certainty).
1 finding from 1 review