Question · asked by 1 review

Acarbose vs no intervention: Development of type 2 diabetes

It is very uncertain whether acarbose changes incidence of T2DM compared with no intervention (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Acarbose vs no intervention
Incidence of T2DM · people at risk of developing type 2 diabetes mellitus
It is very uncertain whether acarbose changes incidence of T2DM compared with no intervention (very low certainty).
Alpha‐glucosidase inhibitors for prevention or delay of type 2 diabetes mellitus and its associated… (2018) · Cochrane Headline outcomes only
RR 0.31 [0.14, 0.69]2 studies · 140 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Alpha‐glucosidase inhibitors for prevention or delay of type 2 diabetes mellitus and its associated complications in people at increased…
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.