Question · asked by 1 review

PRO 140 vs placebo: Individual nadir changes in HIV‐1 RNA level ‐ 2mg/Kg

Population
patients being treated for HIV infection
Intervention
PRO 140
Comparison
placebo
Outcome
Individual nadir changes in HIV‐1 RNA level ‐ 2mg/Kg

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
PRO 140 vs placebo
Individual nadir changes in HIV‐1 RNA level: 2 mg/kg · patients being treated for HIV infection
Humanized PA14 (a monoclonal CCR5 antibody) for treatment of people with HIV infection (2014) · Cochrane Headline outcomes only
no estimate extracted1 study · 19 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Humanized PA14 (a monoclonal CCR5 antibody) for treatment of people with HIV infection
2014 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.