Question · asked by 1 review

Summary of findings: ECM vs a different ECM: Change in weight (kg)

Population
adults and children with cystic fibrosis
Intervention
Summary of findings: ECM
Comparison
a different ECM
Outcome
Change in weight (kg)

Summary of findings: ECM (Creon®) showed no clear difference in change in weight (kg) compared with a different ECM (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Summary of findings: ECM (Creon®) vs a different ECM
Change in weight (kg) · children and adults with cystic fibrosis
Summary of findings: ECM (Creon®) showed no clear difference in change in weight (kg) compared with a different ECM (moderate certainty).
Pancreatic enzyme replacement therapy for people with cystic fibrosis (2020) · Cochrane Headline outcomes only
MD 01 study · 83 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pancreatic enzyme replacement therapy for people with cystic fibrosis
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.