Question · asked by 1 review

Silver diamine fluoride (SDF) vs No biomimetic remineralization (control): Immediate (24 h) resin-dentin bond strength (MPa)

Population
Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro)
Intervention
Silver diamine fluoride (SDF)
Comparison
No biomimetic remineralization (control)
Outcome
Immediate (24 h) resin-dentin bond strength (MPa)

Only one in vitro study assessed a Self-Etch adhesive with the biological ACAD protocol; it was insufficient for network meta-analysis, so no pooled effect estimate is available (ungraded).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Fluoride agent (silver diamine fluoride, SDF) vs No biomimetic remineralization (control)
Immediate (24 h) resin-dentin bond strength (MPa) · Artificial caries-affected dentin (ACAD) in extracted permanent human teeth (in vitro) · 24 h (immediate), In vitro; extracted permanent human teeth; bond strength testing (SBS/microSBS/microTBS), Self-Etch + biological ACAD
Only one in vitro study assessed a Self-Etch adhesive with the biological ACAD protocol; it was insufficient for network meta-analysis, so no pooled effect estimate is available (ungraded).
Biomimetic Remineralization Strategies for Dentin Bond Stability-Systematic Review and Network Meta-Analysis. (2025) All outcomes
Only 1 in vitro study (de Siqueira et al., 2020) assessed Self-Etch adhesive with biological ACAD; insufficient to perform a network meta-analysis, so no pooled estimate is reported.1 studyGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Biomimetic Remineralization Strategies for Dentin Bond Stability-Systematic Review and Network Meta-Analysis.
2025 All outcomes
June 202323Low / Moderate
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.