Question · asked by 1 review

Patient-used 5000 ppm F toothpaste, daily vs 1450 to 1500 ppm F toothpaste: Number of participants with new demineralised lesions (DLs)

Patient-used 5000 ppm F toothpaste, daily throughout treatment showed no clear difference in number of participants with new demineralised lesions (DLs) compared with 1450 ppm F (conventional) toothpaste, daily (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Patient-used 5000 ppm F toothpaste, daily throughout treatment vs 1450 ppm F (conventional) toothpaste, daily
Number of participants with new demineralised lesions (DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond) · At debond; follow-up 1.8 years
Patient-used 5000 ppm F toothpaste, daily throughout treatment showed no clear difference in number of participants with new demineralised lesions (DLs) compared with 1450 ppm F (conventional) toothpaste, daily (low certainty).
Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment (2019) · Cochrane All outcomes
RR 0.68 [0.46, 1.00]1 study · 380 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Fluorides for preventing early tooth decay (demineralised lesions) during fixed brace treatment
2019 · Cochrane All outcomes
1 February 2019list not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.