Question · asked by 1 review
Summary of Findings Table ‐ OnabotulinumtoxinA 20U vs placebo: Total adverse events
- Population
- glabellar lines
- Intervention
- Summary of Findings Table ‐ OnabotulinumtoxinA 20U
- Comparison
- placebo
- Outcome
- Total adverse events
Summary of Findings Table ‐ OnabotulinumtoxinA 20U showed no clear difference in total adverse events compared with placebo (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of Findings Table ‐ OnabotulinumtoxinA 20U vs placebo Total adverse events · glabellar lines Summary of Findings Table ‐ OnabotulinumtoxinA 20U showed no clear difference in total adverse events compared with placebo (low certainty). Botulinum toxin type A for facial wrinkles (2021) · Cochrane Headline outcomes only | RR 1.14 [0.89, 1.45] | 8 studies · 1388 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Botulinum toxin type A for facial wrinkles 2021 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.