Question · asked by 1 review
Pregabalin vs placebo: At least 50% reduction in pain
- Population
- adults with fibromyalgia
- Intervention
- Pregabalin
- Comparison
- placebo
- Outcome
- At least 50% reduction in pain
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Pregabalin vs placebo ‘Substantial benefit’ (at least 50% reduction in pain) · adults with fibromyalgia enrolled in studies of classic design Pregabalin for pain in fibromyalgia in adults (2016) · Cochrane Headline outcomes only | no estimate extracted | 5 studies · 1874 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pregabalin for pain in fibromyalgia in adults 2016 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Pregabalin vs placebo at end of treatment · patients with fibromyalgia · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.