Cetirizine 10 mg/d vs hydroxyzine 25 mg: Withdrawals due to adverse events
Cetirizine 10 mg showed no clear difference in adverse events leading to withdrawal compared with hydroxyzine 25 mg (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Cetirizine 10 mg vs hydroxyzine 25 mg Adverse events leading to withdrawal · patients with chronic spontaneous urticaria Cetirizine 10 mg showed no clear difference in adverse events leading to withdrawal compared with hydroxyzine 25 mg (low certainty). H1‐antihistamines for chronic spontaneous urticaria (2014) · Cochrane Headline outcomes only | RR 0.78 [0.25, 2.45] | 2 studies · 261 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| H1‐antihistamines for chronic spontaneous urticaria 2014 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.