Question · asked by 1 review

Gemcitabine vs Normal saline: Time to recurrence

Gemcitabine showed no clear difference in time to recurrence (absolute effect size estimates based on… compared with saline (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Gemcitabine vs saline
Time to recurrence (absolute effect size estimates based on recurrence rate at 4 years) · participants with non‐muscle invasive bladder cancer (607 men, 127 women)Country: Germany, Turkey, and the US
Gemcitabine showed no clear difference in time to recurrence (absolute effect size estimates based on… compared with saline (low certainty).
Intravesical gemcitabine for non‐muscle invasive bladder cancer (2021) · Cochrane Headline outcomes only
HR 0.77 [0.54, 1.09]2 studies · 734 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Intravesical gemcitabine for non‐muscle invasive bladder cancer
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.