G‐CSF vs placebo or no treatment: Oral mucositis (moderate to severe)
- Population
- Adults with cancer receiving treatment
- Intervention
- G‐CSF
- Comparison
- placebo or no treatment
- Outcome
- Oral mucositis (moderate to severe)
It is very uncertain whether granulocyte-colony stimulating factor (G-CSF) changes oral mucositis (moderate to severe) compared with placebo or no treatment (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Granulocyte-colony stimulating factor (G-CSF) vs Placebo or no treatment Oral mucositis (moderate to severe) · Adults with cancer receiving treatment · Chemotherapy alone for breast cancer It is very uncertain whether granulocyte-colony stimulating factor (G-CSF) changes oral mucositis (moderate to severe) compared with placebo or no treatment (very low certainty). Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and… (2017) · Cochrane All outcomes | RR 0.33 [0.12, 0.95] | 1 study · 14 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors 2017 · Cochrane All outcomes | 2017-05 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- G‐CSF vs placebo/no treatment · Patients with cancer receiving radiotherapy, chemotherapy or targeted therapies · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.