Question · asked by 1 review

Summary of findings ‐ AZLI vs placebo: Participants hospitalised for respiratory exacerbation

Summary of findings ‐ AZLI showed no clear difference in participants hospitalised for respiratory exacerbation compared with placebo (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Summary of findings ‐ AZLI vs placebo
Participants hospitalised for respiratory exacerbation · adults and children with CF
Summary of findings ‐ AZLI showed no clear difference in participants hospitalised for respiratory exacerbation compared with placebo (moderate certainty).
Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis (2021) · Cochrane Headline outcomes only
RR 0.88 [0.53, 1.45]1 study · 100 participantsModerate
Summary of findings ‐ AZLI vs placebo
Participants hospitalised for respiratory exacerbation · adults and children with CF
Summary of findings ‐ AZLI showed no clear difference in participants hospitalised for respiratory exacerbation compared with placebo (moderate certainty).
Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis (2019) · Cochrane Headline outcomes onlyearlier version CD013079.PUB2, superseded
RR 0.88 [0.53, 1.45]1 study · 100 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.