Question · asked by 1 review

H2 receptor antagonists vs placebo: Nausea

H2 antagonists showed no clear difference in reports of nausea compared with placebo (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
H2 antagonists vs placebo
Reports of nausea · people with schizophrenia with antipsychotic‐induced weight gain
H2 antagonists showed no clear difference in reports of nausea compared with placebo (low certainty).
Pharmacological interventions for prevention of weight gain in people with schizophrenia (2022) · Cochrane Headline outcomes only
RR 1.13 [0.34, 3.68]1 study · 175 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pharmacological interventions for prevention of weight gain in people with schizophrenia
2022 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.