Question · asked by 1 review
Prophylactic aciclovir (oral or intravenous) vs Prophylactic valaciclovir (oral): Cost of oral care
- Population
- Patients being treated for cancer (predominantly haematological malignancies)
- Intervention
- Prophylactic aciclovir (oral or intravenous)
- Comparison
- Prophylactic valaciclovir (oral)
- Outcome
- Cost of oral care
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Prophylactic aciclovir (oral or intravenous) vs Prophylactic valaciclovir (oral) Cost of oral care · Patients being treated for cancer (predominantly haematological malignancies) Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer (2009) · Cochrane All outcomes | Only one trial reported on the cost of prophylaxis for HSV (Liesveld 2002). The reported mean pharmacy costs for those randomised to receive aciclovir were $1080 compared to $320 for those initially randomised to… | 1 study · 30 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer 2009 · Cochrane All outcomes | 2008-11 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.