Question · asked by 0 reviews
Deferasirox vs deferoxamine: Overall discontinuation (
- Population
- People with thalassaemia and secondary iron overload
- Intervention
- Deferasirox
- Comparison
- deferoxamine
- Outcome
- Overall discontinuation (
Deferasirox showed no clear difference in discontinuations compared with deferoxamine (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Deferasirox vs Deferoxamine Discontinuations · People with thalassaemia and secondary iron overload Deferasirox showed no clear difference in discontinuations compared with deferoxamine (low certainty). Deferasirox for managing iron overload in people with thalassaemia (2012) · Cochrane Headline outcomes onlyearlier version CD007476.PUB2, superseded | RR 1.19 [0.62, 2.29] | 1 study · 657 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Deferasirox for managing iron overload in people with thalassaemia 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Deferasirox vs deferoxamine · patients with managing transfusional iron overload in people with sickle cell disease · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.