Question · asked by 1 review

Hyperbaric oxygen therapy plus standard care (surgery, antibiotics, oral rinse) vs Standard care alone (surgery, antibiotics, oral rinse): Pain

Population
People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Intervention
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics, oral rinse)
Comparison
Standard care alone (surgery, antibiotics, oral rinse)
Outcome
Pain

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics, oral rinse) vs Standard care alone (surgery, antibiotics, oral rinse)
Pain · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer)… · Weekly (to 16 weeks)
Interventions for treating bisphosphonate‐related osteonecrosis of the jaw (BRONJ) (2016) · Cochrane All outcomes
no estimate extracted1 study · 42 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for treating bisphosphonate‐related osteonecrosis of the jaw (BRONJ)
2016 · Cochrane All outcomes
2015-12Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.