Question · asked by 1 review

Enalapril plus folic acid vs enalapril: Death from any cause

Enalapril plus folic acid showed no clear difference in death from any cause compared with enalapril (high certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Enalapril plus folic acid vs enalapril
Death from any cause · adults with hypertension
Enalapril plus folic acid showed no clear difference in death from any cause compared with enalapril (high certainty).
Homocysteine‐lowering interventions for preventing cardiovascular events (2017) · Cochrane Headline outcomes only
RR 0.94 [0.81, 1.1]1 study · 20702 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Homocysteine‐lowering interventions for preventing cardiovascular events
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.