Question · asked by 1 review

Short‐acting inhaled beta‐2 agonists vs placebo: FEV1 % predicted: absolute change from baseline

It is very uncertain whether short‐acting inhaled beta‐2 agonists changes change from baseline in FEV1 (% predicted) compared with placebo (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Short‐acting inhaled beta‐2 agonists vs placebo
Change from baseline in FEV1 (% predicted) · children and adults with cystic fibrosis
It is very uncertain whether short‐acting inhaled beta‐2 agonists changes change from baseline in FEV1 (% predicted) compared with placebo (very low certainty).
Short‐acting inhaled bronchodilators for cystic fibrosis (2022) · Cochrane Headline outcomes only
no estimate extracted4 studies · 67 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Short‐acting inhaled bronchodilators for cystic fibrosis
2022 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.