Question · asked by 1 review

Benzoyl peroxide vs placebo or no treatment: Total number of participants with any adverse events (long‐term data) Treatment duration: range 10 weeks to 12 weeks

Population
participants with acne
Intervention
Benzoyl peroxide
Comparison
placebo or no treatment
Outcome
Total number of participants with any adverse events (long‐term data) Treatment duration: range 10 weeks to 12 weeks

It is very uncertain whether benzoyl peroxide changes total number of participants with any adverse events (long‐term… compared with placebo or no treatment (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Benzoyl peroxide vs placebo or no treatment
Total number of participants with any adverse events (long‐term data) Treatment duration: range 10 weeks to 12 weeks · acne vulgaris
It is very uncertain whether benzoyl peroxide changes total number of participants with any adverse events (long‐term… compared with placebo or no treatment (very low certainty).
Topical benzoyl peroxide for acne (2020) · Cochrane Headline outcomes only
RR 1.4 [1.15, 1.7]21 studies · 11028 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Topical benzoyl peroxide for acne
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.